助理教授

个人介绍：

蒋灵冬，深圳市海外高层次C类人才，2012年本科毕业于中南大学，硕士毕业于哈尔滨工业大学，师从国家杰青戴志飞教授，2018年获得瑞典隆德大学博士学位，师从分子印迹领域专家叶磊教授，博士毕业后于美国加州大学戴维斯分校（李源培教授课题组，分子自组装和药物递送）和深圳大学（何前军教授课题组，纳米气体药物递送）进行博士后研究，致力于多肽纳米药物和气体纳米药物的癌症精准诊疗研究。

科研项目：

1.中国博士后基金面上项目：化学发光控释CO气体协同化疗药物克服肿瘤多药耐药性的研究，主持。

2.博士后国际交流项目：新型智能纳米聚合物用于蛋白类药物和其他药物的肿瘤靶向递送，主持。

3.广东省基础与应用基础研究基金：化学发光控释CO气体和蛋白药物的纳米胶束用于癌症治疗，主持。

4.国家自然科学基金面上项目：用于调控关节炎微环境的声控催化产氢二维纳米材料的合成与性能研究，参与。

代表成果：

1. Jiang, L.; Chen, D.; Jin, Z.; Xia, C.; Xu, Q.; Fan, M.; Dai, Y.; Liu, J.*; Li Y.*; He, Q.*. Light-triggered nitric oxide release and structure transformation of peptide for enhanced intratumoral retention and sensitized photodynamic therapy. Bioactive Materials, 2022, 12, 303–313.

2. Gong,W.; Jiang, L.; Zhu, Y.; Jiang, M.; Chen, D.; Jin, Z.; Qin, S.; Yu, Z.*; He, Q.*. An activity-based ratiometric fluorescent probe for in vivo real-time imaging of hydrogen molecules, Angewandte Chemie International Edition, 2022, 61, e202114594.

3. Guo, X.;Liu, J.;Jiang, L.;Gong, W.;Wu, H.*; He, Q.*. Sulourea-coordinated Pd nanocubes for NIR-responsive photothermal/H₂S therapy of cancer. Journal of Nanobiotechnology, 2021, 19, 1–14.

4. Jiang, L.; Ye, L.*. Nanoparticle supported temperature responsive polymer brushes for affinity separation of histidine-tagged recombinant proteins. Acta Biomaterialia, 2019, 94, 447–458.

5. Jiang, L.; Lu, R.; Ye, L.*. Towards detection of glycoproteins using molecularly imprinted nanoparticles and boronic acid-modified fluorescent probe. Polymers, 2019, 11, 173.

6. Jiang, L.; Bonde, J.; Ye, L.*. Temperature and pH controlled self-assembly of a protein–polymer biohybrid. Macromolecular Chemistry and Physics, 2018, 1700597.

7. Jiang, L.; Messing, M. E.; Ye, L.*. Temperature and pH dual-responsive core-brush nanocomposite for enrichment of glycoproteins. ACS applied materials & interfaces, 2017, 9, 8985–8995.

8. Jiang, L.; Bagán, H.; Kamra, T.; Zhou, T.; Ye, L.*. Nanohybrid polymer brushes on silica for bioseparation. Journal of Materials Chemistry B, 2016, 4, 3247–3256.

9. Jiang, L.; Hu, L.; Lin, L.; Feng, S.; Li, X.*. The progress of high-intensity focused ultrasound controlled drug delivery. Progress in Modern Biomedicine, 2016, 16, 775–777.

10. Liang, X.; Gao, J.; Jiang, L.; Luo, J.; Jing, L.; Li, X.; Jin, Y.; Dai, Z.*. Nanohybrid liposomal cerasomes with good physiological stability and rapid temperature responsiveness for high intensity focused ultrasound triggered local chemotherapy of cancer. ACS Nano, 2015, 9, 1280–1293.

    联系方式：

    jianglingdong@sztu.edu.cn