助理教授

个人介绍：

深圳技术大学药学院助理教授，硕士生导师，深圳市后备级人才。2017年博士毕业于复旦大学，后于暨南大学从事博士后研究工作，2020年加入深圳技术大学，主要工作领域为基于免疫干预的疾病防治研究，包括新型天然小分子疫苗佐剂的筛选和作用机制，多肽类佐剂的设计合成，肺癌引发树突状细胞失能的机制及新型DC疫苗的构建等，参与和主持了国家自然科学基金、中国博士后科学基金面上资助（一等资助）和深圳市科技计划等科研项目，已发表SCI论文10余篇。

科研项目：

1.中国博士后科学基金面上项目一等资助，肺癌抗原对DC中siglecG通路的作用及机制研究，2018.05 - 2020.03 ，主持

2.深圳市科创委自由探索项目，肺腺癌外泌体CSAG1抗原对树突状细胞siglecG抗原递呈信号通路的作用及机制研究，2019.03 -至今，主持

3.深圳市科技计划基础研究（学科布局），肺癌肿瘤干细胞疫苗的研究，2017.09 - 2020.05，主要参与人

4.国家自然科学基金项目，一种乙肝表面抗原结合蛋白对疫苗的增效剂机理研究，2014.09 - 2017.06 ，主要完成人

5.上海市科委重点科技攻关项目，快速反应增效型狂犬疫苗佐剂的研制，2014.09 - 2017.06 ，主要完成人

代表成果：

1.Zihu Guo, liang han, Yingxue Fu, ziyi wu, yaohua ma, yueping li, haiqing wang, li jiang, shengnan liang, zhenzhong wang, Fu-Rong Li, wei xiao,Jingbo Wang*and Yonghua Wang，Systematic evaluation of the diagnostic and prognostic significance of competitive endogenous RNA networks in prostate cancer，Frontiers in genetics, 2020,doi: 10.3389/fgene.2020.00785.

2.Wang, J., Y. Wang, L. Han,M.Shahen, C. Hu and F. Li.Multi-omics integration reveals a competitive endogenous RNAs network for the identification of progression biomarkers and the stratification of patients diagnosed with nephroblastoma. Frontiers in oncology. 2020, 10,doi: 10.3389/fonc.2020.00444.

3.Wang, J., Shao, L., Wu, L., Ma, W., Zheng, Y., Hu, C. and Li F.,Expression levels of a gene signature in hiPSC associated with lung adenocarcinoma stem cells and its capability in eliciting specific anti-tumor immune-response in a humanized mice model.Thoracic Cancer. 2020, 39,43，doi:10.1111/1759-7714.13440.

4.Wang, J.B., X. Huang, and F.R. Li, Impaired dendritic cell functions in lung cancer: a review of recent advances and future perspectives. Cancer Commun (Lond), 2019. 39(1): p. 43.

5.Wang, J., et al., Systems Pharmacology-based strategy to screen new adjuvant for hepatitis B vaccine from Traditional Chinese Medicine Ophiocordyceps sinensis. Sci Rep, 2017. 7: p. 44788.

6.Wang, J.,et al., A Pre-Clinical Safety Evaluation of SBP (HBsAg-Binding Protein) Adjuvant for Hepatitis B Vaccine. PLoS One, 2017. 12(1): p. e0170313.

7.Liu, R.#,Wang, J.#,et al., A novel rabies virus lipopeptide provides a better protection by improving the magnitude of DCs activation and T cell responses. Virus Res, 2016. 221: p. 66-73.

8.RuiLiu,JingboWang,YanYang,InamullahKhan,NaishuoZhu,Rabies virus lipopeptide conjugated to a TLR7 agonist improves the magnitude and quality of the Th1-biased humoral immune response in mice,Virology 497(2016)102–110.

9.Fei He†, Ning Li†, Hai-Bo Huang,Jing-Bo Wang, Xiao-Fei Yang, Hua-DongWang, Wei Huang andFu-Rong Li，LSD1 inhibition yields functional insulin-producingcells from human embryonicstem cells，Cell Research & Therapy (2020) 11:163。

10.Ce Wang, Xue Huang, Yingjuan Wu,Jingbo Wang,Furong Li, Guoqing Guo，Tumor Cell-associated Exosomes Robustly ElicitAnti-tumor Immune Responses through ModulatingDendritic Cell Vaccines in Lung Tumor，Int. J. Biol. Sci. 2020; 16(4): 633-643.*

联系方式：

wangjingbo@sztu.edu.cn