助理教授
个人介绍:
孙长利,助理教授,博士毕业于中国科学院昆明植物研究所药物化学专业,后于中国科学院南海海洋研究所从事研究工作,历任博士后、助理研究员、副研究员、硕士生导师。2024年7月加入深圳技术大学药学院,主要从事海洋微生物天然产物及其生物合成研究;已发表SCI论文40余篇。授权国家发明专利5件,主持国家自然科学基金面上项目和青年基金项目等6项。
主持项目:
1. 国家自然科学基金面上项目(22177117),主持,60.0万元,2022.01-2025.12.
2. 广东省自然科学基金面上项目(2023A1515011303),主持,10.0万元. 2023.01-2025.12.
3. 国家自然科学基金青年基金项目(41706169),主持,25.0万元,2018.01-2020.12.
4. 省级促进经济高质量发展专项资金项目子课题(2020032),主持,130.0万元,2020.01-2022.01.
5. 第60批中国博士后科学基金面上资助一等资助 (2016M600691),主持,8.0万元,2016.08-2018.08.
6. 2016年度支持“率先行动”中国博士后科学基金会与中国科学院联合资助优秀博士后项目(2016LH00024),主持,20.0 万元,2016.08-2018.08.
部分文章:
(1) Sun C., Yang Z., Zhang C., Liu Z., He J., Liu Q., Zhang T., Ju J.,* Ma J.* Genome mining of Streptomyces atratus SCSIO ZH16: discovery of atratumycin and identification of its biosynthetic gene cluster. Org. Lett. 2019, 21:1453–1457.
(2) Govindarajan G., Yao Z., Zhou Z., Zheng X., Ma J., Kumar P.S., Ju J., Sun C.* Genome sequencing of Streptomyces griseus SCSIO PteL053, the producer of 2,2’-bipyridine and actinomycin analogs, and associated biosynthetic gene cluster analysis. J. Mar. Sci. Eng. 2023, 11: 396.
(3) Sun C., Liu Z. (Co-first author), Zhu X., Huang H., Wu Q., Zheng X., Qin X., Zhang T., Ju J. *, Ma J.* Anti-tubercular ilamycins from marine-derived Streptomyces atratus SCSIO ZH16 ∆ilaR. J. Nat. Prod. 2020, 83: 1646–1657.
(4) Yao Z., Sun C (Co-first author), Xia Y., Wang F., Fu L., Ma J., Li Q., Ju J. Mutasynthesis of antibacterial aalogenated actinomycin analogues. J. Nat. Prod. 2021, 84: 2217-2225.
(5) Yang Z., Sun C. (Co-first author), Liu Z., Liu Q., Zhang T., Ju J.*, Ma J.* Production of antitubercular depsipeptides via biosynthetic engineering of cinnamoyl units. J. Nat. Prod. 2020, 83, 5, 1666-1673.
(6) Sun C., Zhang C., Qin X., Wei X., Liu Q., Li Q., Ju J.* Genome mining of Streptomyces olivaceus SCSIO T05: discovery of olimycins A and B and assignment of absolute configurations. Tetrahedron 2018, 74:199-203.
(7) Zhou Z., Wu Q., Xie Q., Ling C., Zhang H., Sun C.,* Ju J.* New borrelidins from Onchidium sp. associated Streptomyces olivaceus SCSIO LO13. Chem. Biodivers. 2020, 17: e1900560.
(8) Meng L., Sun C. (Co-first author), Zhang C., Song S., Sun X., Ju J., Deng Y*. Efficacy of compounds isolated from Streptomyces olivaceus against the morphogenesis and virulence of Candida albicans. Mar. Drugs. 2019, 17: 442
(9) Sun C., Geng C., Huang. X., Ma. Y., Zheng. X., Yang. T., et al. Bioassay-guided isolation of saikosaponins with agonistic activity on 5-hydroxyptamine 2C receptor from Bupleurum chinense and their potential use for the treatment of obesity. Chin. J. Nat. Med. 2017, 15:467-473.
(10) Sun C., Geng C., Chen. X., Yang. T., Huang. X., Ma. Y., et al. LC-MS guided isolation of ent-kaurane doterpenoids from Nouelia insignis. Fitoterapia. 2016, 111:42-48.
联系方式:sunchangli@sztu.edu.cn