助理教授

个人介绍：

潘正银，助理教授，硕士生导师，深圳市“鹏城孔雀计划”特聘岗位人才(C类)。2020年获得中山大学博士学位，导师毛宗万教授。研究领域：金属药物化学和金属化学生物学。目前已经发表SCI论文30余篇，其中以第一作者或通讯作者发表SCI论文18篇，申请专利7项。主持国家自然科学基金青年项目和中国博士后科学基金面上项目，并参与多项国家和省市级重点项目。

科研项目：

国家自然科学基金青年基金项目：铁稳态调控的金属药物设计合成及抗肿瘤机制研究，2022/01-2024/12, 30万，主持，在研。

中国博士后科学基金面上资助项目：碳酸酐酶IX靶向激活磷光金属配合物的抗肿瘤机制研究，2021.06-2023.02, 8万，主持，已结题。

代表论文：

1. 1.Xiaoyu Xu, Meixu Chen, Shan Jiang,Zheng-Yin Pan*, Chunshun Zhao*. Endoplasmic Reticulum-Targeting Iridium(III) Nanosonosensitizer Amplifies Immunogenic Cell Death for Boosted Tumor Sono-Immunotherapy.Adv. Funct. Mater.,2024, 2314780. (IF=19.0)

2. 2.Xiaoyu Xu, Jinling Zheng, Na Liang, Xu Zhang, Shayibai Shabiti, Zixi Wang, Shiwen Yu,Zheng-Yin Pan*, Wenjun Li*, Lintao Cai*.Bioorthogonal/Ultrasound Activated Oncolytic Pyroptosis Amplifies In Situ Tumor Vaccination for Boosting Antitumor Immunity.ACS Nano,2024, 18, 9413-9430. (IF=17.1)

3. 3.Xiaoyu Xu, Shayibai Shabiti, Xu Zhang, Jinling Zheng, Na Liang, Zixi Wang, Shiwen Yu, Yujue Wang, Shan Jiang,Zheng-Yin Pan*, Wenjun Li*, Lintao Cai*. Membrane-anchoring clickable Iridium(III) nanosonosensitizer in situ evokes PANoptosis for augmented tumor sono-immunotherapy.Nano Today,2024, 56, 102270. (IF=17.4)

4. 4.Yu-Yi Ling, Ya-Jie Kong, Liang Hao,Zheng-Yin Pan*, Zong-Wan Mao*, Cai-Ping Tan*.Photodegradation of carbonic anhydrase by iridium complexes for induction of immunogenic cell death under hypoxia.Inorg. Chem. Front.,2023,10, 3284-3292.(IF=7.0)

5. 5.Zheng-Yin Pan¹, Yu-Yi Ling¹, Hang Zhang, Liang Hao, Cai-Ping Tan*, Pt(IV)-Deferasirox Prodrug Combats DNA Damage Repair by Regulating RNA N6-Methyladenosine Methylation.J. Med. Chem.,2022, 65, 14692-14700. (IF=7.3)

6. 6.Zheng-Yin Pan, Cai-ping Tan*, Lu-Si Rao, Hang Zhang, Yue Zheng, Liang Hao, Liang-Nian Ji, Zong-Wan Mao*.Recoding the Cancer Epigenome by Intervening in Metabolism and Iron Homeostasis with Mitochondria-Targeted Rhenium(I) Complexes.Angew. Chem. Int. Ed.,2020, 59, 18755-18762.(IF=16.6)

7. 7.Qian Cao^1,Dan-jie Zhou¹,Zheng-Yin Pan¹(co-first), Gang-Gang Yang, Hang Zhang, Liang-Nian Ji, Zong-Wan Mao*.CAIXplatins: Highly Potent Platinum(IV) Prodrugs Selective Against Carbonic Anhydrase IX for the Treatment of Hypoxic Tumors.Angew. Chem. Int. Ed.,2020, 59, 18556-18562. (IF=16.6)

8. 8.Gui-Yang Yao¹,Zheng-Yin Pan¹(co-first), Chun-Lei Wu, Wei Wang, Li-Jing Fang*, and Wu Su*. Efficient Synthesis and Stereochemical Revision of Coibamide A.J. Am. Chem. Soc.,2015, 137, 13488−13491. (IF=15.0)

联系方式：

panzhengyin@sztu.edu.cn